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Isabel Kleefeld was born in Düsseldorf. She financed her studies at Berlin’s Free University and the University of Arts (HdK) by working as an editorial assistant at broadcaster SFB and later as a production assistant and script/continuity consultant on various films. After graduation in 1993, she worked as a first AD for such colleagues as Detlev Buck, Sönke Wortmann, Lars Becker and Oliver Hirschbiegel before making her directorial debut in 2001 with the TV film SCHLUSS MIT LUSTIG, which earned third place in Studio Hamburg’s Young Director’s Prize. Her 2004 TV film DAS GESPENST VON CANTERVILLE was nominated at the 2005 German Television Prize and won the Bavarian Television Award for Best Director. In 2007, she was awarded the Adolf Grimme Prize for her screenplay and direction of ARNIE'S WORLD (ARNIES WELT). Her other films include: MURDER ON PRESCRIPTION (MORD AUF REZEPT, TV, 2005), UNDER SUSPICION: A NEW LIFE (UNTER VERDACHT – EIN NEUES LEBEN, TV, 2006), UNDER SUSPICION: THE WRONG WOMAN (UNTER VERDACHT – DIE FALSCHE FRAU, TV, 2008), SLEEPLESS (SCHLAFLOS, TV, 2008), MOM'S COMING (MAMA KOMMT!, TV, 2008), FROG QUEENS (FROSCHKÖNIGINNEN, TV, 2009), and GLORY: A TALE OF MISTAKEN IDENTITIES (RUHM, 2011).